Biological
Female sex
Atopic dermatitis
Childhood eczema
Low age at onset of hand eczema
Genetic mutations
Contact allergy
Talk to the hand
You know it’s chronic hand eczema (CHE) when the eczema on your patients’ hands and wrists has
lasted for
MORE THAN
3 MONTHS1
relapsed
MORE THAN
TWICE A YEAR1
Dr. Adrian Rodriguez, MD, talks CHE Disease State
What is CHE? How prevalent is it? What is its pathophysiology? Watch to learn the fundamentals of this disease.
Chronic hand eczema is not an uncommon skin disease, with an overall self-reported physician-diagnosed prevalence of 4.7% in the general population.2,3
Patients with CHE may present with multiple subtypes, including atopic dermatitis.1
TALKING THE TALK ABOUT CHE
Chronic hand eczema expresses itself in a language all its own, with signs and symptoms that include4
Joseph Gorelick, FNP-C, talks CHE Signs and Symptoms
How does CHE differ from atopic dermatitis of the hands? Get to know the typical signs and distinguishing features of this disease.
HANDS EXPOSED
Our hands are part of everything we do. We use them to greet people, perform everyday tasks, and express our emotions. However, our hands are exposed to water from handwashing throughout the day, as well as cleaning agents that can irritate the skin.1,5,6
For your patients with chronic hand eczema, that exposure presents the additional challenge of a large treatment gap,
because no FDA-approved CHE treatments exist.7
RISK FACTORS IN CHE1
Environmental
Wet work
Occupational or domestic exposure (prolonged exposure to irritants)
Climate (cold/dry conditions)
Lifestyle
Tobacco use
Stress
Dr. Omar Noor, MD, FAAD, talks CHE Disease Impact
What are the risk factors of CHE? Are certain people or certain occupations more susceptible than others? Watch to find out.
STRAIGHT TALK ABOUT CHRONIC HAND ECZEMA
While the most common symptoms of chronic hand eczema are itch and pain, the disease greatly affects physical functioning. Holding and even just touching everyday objects can be challenging and frustrating to someone with moderate-to-severe CHE.4,5
Patients with CHE also report that their disease causes them to be absent from their jobs, avoid certain activities while at work, and even take more breaks from tasks so they can administer their therapy.4
“When there are cracks, even at work and all, it also hurts when you move the hands.”
— Patient with CHE8
CHE negatively impacts patients’ quality of life, often bringing on5,9
Anxiety
Low self-esteem
Social phobia
Embarrassment
Self-isolation
AMONG PEOPLE AFFLICTED WITH CHE10
76%...reported it affected their social or leisure activities
38%...felt it impacted their engagement in activities
79%...stated it had a negative effect on their mood
“If my hands and fingers clear up completely, then I will be able to play the guitar again.”
— Patient with CHE8
KNOW CHE LIKE THE BACK OF YOUR HAND
References: 1. Thyssen JP, et al. Contact Dermatitis. 2022;86(5):357-378. doi:10.1111/cod.14035 2. Lee GR, et al. Dermatol Ther. 2019;32(3):e12840. doi:10.1111/dth.12840 3. Apfelbacher C, et al. Prevalence of chronic hand eczema in adults: A cross sectional multi-national study of over 60,000 respondents in the general population. Poster presented at: The Congress of the European Society of Contact Dermatitis (ESCD); September 4-7, 2024; Dresden, Germany. 4. Grant L, et al. Adv Ther. 2020;37(2):692-706. doi:10.1007/s12325-019-01164-5 5. Lynde C, et al. J Cutan Med Surg. 2010;14(6):267-284. doi:10.2310/7750.2010.09094 6. Mirabelli MC, et al. Contact Dermatitis. 2012;66(4):188-196. doi:10.1111/j.1600-0536.2011.02023.x 7. Dubin C, et al. Ther Clin Risk Manag. 2020;16:1319-1332. doi:10.2147/TCRM.S292504 8. Rönsch H, et al. J Eur Acad Dermatol Venereol. 2023;37(7):1396-1405. doi:10.1111/jdv.19055 9. Agner T, et al. J Eur Acad Dermatol Venereol. 2020;34(suppl 1):4-12. doi:10.1111/jdv.16061 10. Ahmed A, et al. Clin Exp Dermatol. 2015;40(5):495-501. doi:10.1111/ced.12619